Perluxan® is a clinically studied extract of hops specifically developed to promote joint health. In a randomized, double-blind placebo controlled trial of 36 subjects, the benefits of Perluxan® on joint comfort reached statistical significance within two hours of the first dose and were sustained over the 14-day period. Perluxan® is free of sleep-inducing and phytoestrogenic compounds typically associated with hops extracts. The alpha and iso-alpha acids in Perluxan® maintain healthy NF-kappaB-associated expression of COX-2 and cytokines such as IL-6 and TNFα in connective tissue. Curcumin complements Perluxan® through its extensively characterized effects on cytokine-mediated signal transduction, matrix metalloproteinase (MMP) expression and multiple components of the arachidonic acid cascade. Curcumin C3 Complex® is the subject of extensive ongoing clinical investigations at numerous hospitals and universities. Ginger promotes joint health through maintaining healthy cytokine signaling in cartilage and the synovium. 5-LOXIN® boswellia serrata extract provides the highly bioactive triterpenoid AKBA, which supports connective tissue structural composition and comfort through supporting healthy immune responses, 5-lipoxygenase activity and synovial matrix metalloproteinase 3 (MMP-3) levels. In a 3-month double-blind, placebo-controlled study of 75 subjects, significant functional support and comfort scores were evident as early as day 7.
Phyto-4 is a powerful combination of clinically researched botanicals that maintain tissue health by targeting immune mediators, eicosanoids and proteases.
The Perluxan® trademark is used with permission.
Curcumin C3 Complex® is a registered trademark and patented product of Sabinsa Corporation.
5-LOXIN® is a registered trademark of PL Thomas - Laila Nutra, LLC and is used under license. International Patents Pending.
These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious condition.